Yersinia ruckeri infection in Atlantic salmon brackish water recirculating aquaculture system
Etterevaluering
Mattilsynet er forpliktet etter regelverket til å etterevaluere alle forsøk som er betydelig belastende for forsøksdyrene.
Begrunnelse for etterevalueringen
Infection was performed in RAS, though it did not result in the expected mortality. The pathogen could not establish in the system and might offer insight why there was no mortality. Nonetheless, new insights into the effects of feed and infection on system microbiota and host immune response were generated.
900 fish were used in the study where 600 experienced mild while 300 experienced moderate distress.
No alternative in vitro models are available at the moment to answer the objective of the trial. Previous experience of the model and the system was crucial in carrying out the trial.
900 fish were used in the study where 600 experienced mild while 300 experienced moderate distress.
No alternative in vitro models are available at the moment to answer the objective of the trial. Previous experience of the model and the system was crucial in carrying out the trial.